During the last coupple of years several important publications have shed light on protein Nt-acetylation: cellular and biochemical function, substrates, and physiological and pathological significanse.
In a new review published in Trends in Biochemical sciences we give an overview over these findings. Find the review here.
Scientific projects
Inflammatory cell death mechanisms
Research project funded by The Norwegian Cancer Society, 2016-18. CEMIR, NTNU.
Inflammatory cell death in bacterial infections.
With Egil Lien (University of Massachusetts) Terje Espevik (NTNU).
Drug resistance mechanisms in multiple myelomatosis.
With Geir Bjørkøy and Anders Sundan (NTNU).
Cellular functions of Nt-acetylation.
With Thomas Arnesen (University of Bergen), Petra van Damme and Kris Gaevart (University of Ghent).
Philosophical projects
Knowledge production in experimental life sciences.
Conceptual biology.
Publications
- Aksnes et al. An organellar Na-acetyltransferase, Naa60, acetylates cytosolic N-termini of transmembrane proteins and maintains Golgi-integrity, Cell Reports 2015
- Starheim et al. Protein Nt-acetyltransferases: when the start matters TiBS 2012 Chosen among Top10 Ed Board favorite articles 2012
- Arnesen et al. - The chaperone-like protein HYPK acts together with NatA in cotranslational N-terminal acetylation and prevention of Huntingtin aggregation, MCB 2010
- Starheim & Gromyko et al. - Composition and biological significance of the human Nα-terminal acetyltransferases, BMC Proceedings 2009
- Arnesen et al. - A novel human NatA Nα-terminal acetyltransferase complex: hNaa16p-hNaa10p (hNat2-hArd1), BMC 2009
- Starheim et al. - Knockdown of Human Nα-Terminal Acetyltransferase Complex C Leads to p53-Dependent Apoptosis and Aberrant Human Arl8b Localization, MCB 2009
- Starheim et al. - Identification of the human Nα-acetyltransferase complex B (hNatB): a complex important for cell-cycle progression, Biochemical J. 2008
CV
Employment
- 2016 - : Researcher, The Norwegian Cancer Society Young Researcher Qualifying Grant. CEMIR, NTNU Trondheim Norway.
- 2013 - 2015 : Post doctoral researcher, CEMIR, NTNU Trondheim Norway and UMass Medical School, Worcester MA USA.
- Aug-Des. 2012 : Researcher, K.G. Jebsens center for myeloma research and the Autophagy group, NTNU Trondheim Norway.
- 2010 - 2012: Researcher, Dep. Surgical Sciences & Dep. Molecular Biology, University of Bergen
- Feb. 2011 - July 2011 : Guest researcher Early Fly Development Group, Instituto Gulbenkian de Ciençia, Oeiras Portugal.
- 2007-2008: Scientific assistant, University of Bergen
- 2008-2011: M. Phil Philosophy, University of Bergen
- 2008-2010: PhD Department of Surgical Sciences, University of Bergen
- 2005-2007: M.Sc. Molecular biology, University of Bergen
- 2002-2007: Lower-degree studies Philosophy, University of Bergen
- 2002-2005: BSc Molecular Biology, University of Bergen
- 2009-20010 : Comitee for recruitment to research education, University of Bergen
- 2005, 2009- : Department board, Department of Molecular Biology, University of Bergen
- 2005-2006: Board-member Students Society of Bergen
Other
- Ad hoc reviewer for international research journals
- Supervision of bachelor and master students
- Teaching and external sensor in research ethics and philosphy of science (University of Bergen)
Journal
New and old news
torsdag 8. mars 2012
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